CC Founder Characterization
• Proteomic profiling in islets collected from male and female CC founder mice maintained on HFD for 16 weeks.
• Genome-wide RNA profiling in islets collected from male and female CC founder mice maintained on HFD for 16 weeks.
• Genome-wide RNA profiling in liver collected from male CC founder mice maintained on either chow diet or HFD for 22 weeks.
• Plasma levels of acyl-carnitines and amino acids from male CC founder mice maintained on either chow diet or HFD for 22 weeks.
• Liver levels of acyl-carnitines, amino acids and organic acids from male CC founder mice maintained on either chow diet or HFD for 22 weeks.
• Muscle levels of acyl-carnitines, amino acids and organic acids from male CC founder mice maintained on either chow diet or HFD for 22 weeks.
• Genome-wide RNA profiling in perigonadal white adipose tissue (WAT) collected from male and female CC founder mice maintained on HFD for 16 weeks.